KMID : 0606420080140030189
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Korean Journal of Women Health Nursing 2008 Volume.14 No. 3 p.189 ~ p.195
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Factors of Occurrence of Amenorrhea and Climacteric Symptoms in Breast Cancer Patients Underwent Chemotherapy
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Chang Soon-Bok
Lee Kyung-Hi Chung Chae-Weon
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Abstract
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Purpose:This study aimed to investigate the factors of occurrence of amenorrhea and the severity of climacteric symptoms in breast cancer patients who underwent chemotherapy.
Method:Women diagnosed with breast cancer without metastasis or recurrence, had surgery followed by chemotherapy, and hadmenses at the time of surgery were recruited from S hospital located in Seoul. A total of 99 women aged 31 thru 55 years participated and filled out a structured questionnaire including the Functional Assessment Cancer Therapy-Breast plus Endocrine Symptom when they visited the clinic for follow-up.
Result:In 88 women amenorrhea occurred within an average of 2 months since beginning chemotherapy, and menstruation was resumed in only 11 women. About 98% of women aged over 40 experienced a cessation in menses thus age was an apparent factor of amenorrhea (Exp(B)=.76, p<.05). Presence of chronic disease (©¬=.25, p<.05) and body weight change (©¬=.30, p<.01) were significant factors influencing the severity of climacteric symptoms.
Conclusion:Nurses need to have clinical evidences of menstrual changes due to breast cancer treatment. Information about premature menopause and climacteric symptoms should be provided according to women¡¯s health conditions so that they cope better during their survival.
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KEYWORD
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Breast cancer, Chemotherapy, Amenorrhea, Climacteric
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